Extrapulmonary, draining lesions (including scrofula) |
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Discontinue isolation only when patient is improving clinically, and drainage has ceased or there are three consecutive negative cultures of continued drainage. Examine for evidence of active pulmonary tuberculosis.
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Pulmonary (suspected or confirmed) OR laryngeal disease |
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AFB smear positive:
Min 14d tx and meets discontinuation criteria
AFB smear neg, high suspicion and started on therapy:
Min 5d tx and meets discontinuation critera;
AFB smear neg, low suspicion and not on therapy:
meets discontinuation criteria
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Collect 3 separate AFB sputum obtained at 8-12 hr intervals (at least 1 specimen must be in early AM). See
1. https://infectioncontrol.ucsfmedicalcenter.org/tb-algorithm
2. Environment of Care Manual for Aerosol Transmissible Disease Exposure Control Plan.
Discuss with HEIP before discontinuing airborne isolation
AFB smear-positive:
• 14 days of anti-TB treatment AND
• AFB smear negative x 3 AND
• Clinically improving
AFB smear-negative:
• At least 5 days of anti-TB treatment AND
• Clinically improving
High risk for MDR TB and either AFB smear-negative or smear-positive:
• Discuss with HEIP
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